Krall A, Spring-Mills E
Arch Androl. 1981 Jun;6(4):295-300. doi: 10.3109/01485018108987540.
The effects of bromocriptine and perphenazine on C3H/HeJ mouse seminal vesicles were studied. The response of the stroma and parenchyma of the glands to the hormones differed. Testosterone repressed stromal proliferation. Prolactin had no observable stromal effect but influenced the response of the parenchyma. In castrated mice, low levels of prolactin were associated with abnormal epithelial mitotic activity and atypical cytology while elevated prolactin levels resulted in a nonatrophic epithelium similar to that from the seminal vesicles of intact individuals. In the absence of testicular testosterone, prolactin may exert an inhibitory influence on glandular proliferation.
研究了溴隐亭和奋乃静对C3H/HeJ小鼠精囊的影响。腺体的基质和实质对激素的反应不同。睾酮抑制基质增殖。催乳素对基质无明显影响，但影响实质的反应。在去势小鼠中，低水平的催乳素与上皮有丝分裂活动异常和非典型细胞学有关，而催乳素水平升高则导致上皮无萎缩，类似于完整个体精囊的上皮。在没有睾丸睾酮的情况下，催乳素可能对腺体增殖产生抑制作用。
