Brody S A, Russell W G, Krantz S B, Graber S E
Arch Intern Med. 1981 Jul;141(8):1080-1.
A patient with leukemic reticuloendotheliosis had splenomegaly, neutropenia, and a severe underproduction anemia. During a three-year period, the hematocrit was never in the normal range, and periodic transfusions were required. However, after an episode of hepatitis that was positive for B surface antigen, the spleen became smaller, the number of neutrophils increased, the transfusion requirement disappeared, and the hematocrit rose to normal. Several mechanisms for this observation are proposed.
一名患有白血病性网状内皮细胞增多症的患者出现脾肿大、中性粒细胞减少和严重的生成不足性贫血。在三年期间,血细胞比容从未处于正常范围,需要定期输血。然而,在一次乙型肝炎表面抗原呈阳性的肝炎发作后,脾脏变小,中性粒细胞数量增加,输血需求消失,血细胞比容升至正常。针对这一观察结果提出了几种机制。