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[意大利破伤风流行病学。针对普通人群的强制性主动预防措施]

[Epidemiology of tetanus in Italy. Compulsory active preventive measures for the general population].

作者信息

Giannico L, Ballada D

出版信息

Boll Ist Sieroter Milan. 1980 Nov 30;59(5):397-404.

PMID:7248068
Abstract

Tetanus mortality in Italy shows a constant and significant decrease after the second World War period. In particular, it is diminished the male mortality for the ages between 20 and 60 yrs, with inversion of the M/F rate. Morbidity rates show a similar pattern since 1955 when notification of new cases of tetanus became compulsory. Active prophylaxis policy against tetanus includes compulsory vaccination of the draftees (since 1939 and '40), of high risk workers and athletes (since 1963), and of all newborns in their second year of life (since 1968). Subsequent booster vaccine administrations are performed every four years. A law which anticipates the start of the vaccination at the third month of life is going to be approved. Epidemiological considerations, data from literature and experimental data suggest the opportunity of further modifications.

摘要

意大利的破伤风死亡率在第二次世界大战后持续显著下降。特别是,20至60岁男性的死亡率有所降低,且男女死亡率之比出现了反转。自1955年破伤风新病例报告成为强制性要求以来,发病率也呈现出类似的模式。破伤风主动预防政策包括对新兵(自1939年和1940年起)、高危工人和运动员(自1963年起)以及所有一岁儿童(自1968年起)进行强制接种。随后每四年进行一次加强疫苗接种。一项将接种起始时间提前至出生后第三个月的法律即将获批。流行病学考量、文献数据和实验数据表明有进一步调整的必要性。

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