Rosmini F, Gentili G, Wirz M, Collotti C, Panà A, Terzi I, Conti S, Pasquini P
Department of Epidemiology and Biostatistics, Istituto Superiore di Sanità, Rome, Italy.
Eur J Epidemiol. 1987 Sep;3(3):302-7. doi: 10.1007/BF00149740.
Systematic mandatory immunization of children against tetanus begun in Italy in 1968. Preceding birth cohorts, accounting for almost 80% of present Italian population, were poorly immune or totally non-immune; around 90% of cases of tetanus occurring in Italy in recent years are observed among them. In a national sample of 4770 young males born between 1956 and 1963, about one third was not protected. Prevalence of non-immune subjects was greater in the Southern Regions and the Islands, in rural areas, among the unemployed, among the older birth cohorts.
1968年意大利开始对儿童进行系统性破伤风强制免疫。在当前意大利人口中占近80%的之前出生队列免疫能力较差或完全没有免疫力;近年来在意大利发生的破伤风病例中,约90%出现在这些人群中。在一个由4770名1956年至1963年出生的年轻男性组成的全国样本中,约三分之一没有受到保护。南部地区和岛屿、农村地区、失业人群以及较早出生队列中的非免疫人群患病率更高。