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非甾体抗炎药和各种类固醇对豚鼠离体回肠中蛙皮素和雨蛙肽诱导的收缩的抑制作用及其被前列腺素E1逆转的作用。

Inhibition of caerulein and physalaemin-induced contractions of guinea-pig isolated ileum by non-steroidal antiinflammatory drugs and various steroids and their reversal by prostaglandin E1.

作者信息

Fontaine J, Famaey J P, Seaman I, Reuse J

出版信息

Prostaglandins Med. 1978 Nov;1(5):351-7. doi: 10.1016/0161-4630(78)90122-2.

Abstract

Two non-steroidal antiinflammatory drugs, two antiinflammatory steroids and two sex steroids were found to potently and reversibly inhibit caerulein-induced and physalaemin-induced contractions of guinea-pig isolated ileum. The effects of these drugs were reversed by small amounts of PGE1.

摘要

发现两种非甾体抗炎药、两种抗炎类固醇和两种性激素能有效且可逆地抑制豚鼠离体回肠中蛙皮素诱导和雨蛙肽诱导的收缩。这些药物的作用可被少量前列腺素E1逆转。

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