Lefèbvre P J, Luyckx A S
Prostaglandins Med. 1978 Nov;1(5):419-20. doi: 10.1016/0161-4630(78)90128-3.
The canine gastric fundus has recently been demonstrated to contain and release a material identical by all criteria to pancreatic glucagon (1, 2). Since exogenous prostaglandins have been reported to stimulate pancreatic glucagon release (3) and endogenous prostaglandins are suspected to play a role in the control of glucagon secretion (4), we were interested in seeing if prostaglandin E1 (PGE1) would affect gastric-glucagon release.
最近已证实犬胃底含有并释放一种在所有标准上都与胰高血糖素相同的物质(1,2)。由于据报道外源性前列腺素可刺激胰高血糖素释放(3),并且怀疑内源性前列腺素在胰高血糖素分泌的控制中起作用(4),我们有兴趣了解前列腺素E1(PGE1)是否会影响胃胰高血糖素的释放。