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Covalent binding of methotrexate to immunoglobulins and the effect of antibody-linked drug on tumor growth in vivo.

作者信息

Kulkarni P N, Blair A H, Ghose T I

出版信息

Cancer Res. 1981 Jul;41(7):2700-6.

PMID:7248938
Abstract
摘要

相似文献

1
Covalent binding of methotrexate to immunoglobulins and the effect of antibody-linked drug on tumor growth in vivo.甲氨蝶呤与免疫球蛋白的共价结合及抗体连接药物对体内肿瘤生长的影响。
Cancer Res. 1981 Jul;41(7):2700-6.
2
The covalent binding of daunomycin and adriamycin to antibodies, with retention of both drug and antibody activities.
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Antibodies as carriers of cancer chemotherapeutic agents.作为癌症化疗药物载体的抗体。
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Use of antibodies against tumor-associated antigens for cancer diagnosis and treatment.使用针对肿瘤相关抗原的抗体进行癌症诊断和治疗。
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In vivo and in vitro effects of tumour specific antibodies with chlorambucil.肿瘤特异性抗体与苯丁酸氮芥的体内和体外效应
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The effect in vivo of chemotherapeutic drug--antibody conjugates in two murine experimental tumor systems.化疗药物-抗体偶联物在两种小鼠实验性肿瘤系统中的体内效应。
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The metabolism of different immunoglobulin classes in irradiated mice. IV. Fate of circulating IgA of tumour or transfusion origin.受辐照小鼠体内不同免疫球蛋白类别的代谢。IV. 肿瘤来源或输血来源的循环IgA的去向。
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Uptake of methotrexate linked to an anti-EL4-lymphoma antibody by EL4 cells.甲氨蝶呤与抗EL4淋巴瘤抗体的结合被EL4细胞摄取。
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7
Conjugation of methotrexate to IgG antibodies and their F(ab)2 fragments and the effect of conjugated methotrexate on tumor growth in vivo.甲氨蝶呤与IgG抗体及其F(ab)2片段的偶联以及偶联的甲氨蝶呤对体内肿瘤生长的影响。
Cancer Immunol Immunother. 1985;19(3):211-4. doi: 10.1007/BF00199228.
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Carbohydrate-binding proteins of tumor lines with different growth properties. II. Changes in their pattern in clones of transformed rat fibroblasts of differing metastatic potential.
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