• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Alkylation of nucleic acids and metabolism of small doses of dimethylnitrosamine in the rat.

作者信息

Pegg A E, Perry W

出版信息

Cancer Res. 1981 Aug;41(8):3128-32.

PMID:7248969
Abstract
摘要

相似文献

1
Alkylation of nucleic acids and metabolism of small doses of dimethylnitrosamine in the rat.大鼠体内核酸的烷基化作用及小剂量二甲基亚硝胺的代谢
Cancer Res. 1981 Aug;41(8):3128-32.
2
Metabolism of dimethylnitrosamine and subsequent removal of O6-methylguanine from DNA by isolated rat hepatocytes.二甲基亚硝胺的代谢以及分离的大鼠肝细胞随后从DNA中去除O6-甲基鸟嘌呤的过程。
Chem Biol Interact. 1981 Jan;33(2-3):229-38. doi: 10.1016/0009-2797(81)90043-0.
3
[DNA alkylation during endogenous synthesis of N-nitrosodimethylamine].
Eksp Onkol. 1987;9(1):11-4.
4
Alkylating intermediates in nitrosamine metabolism.
Biochem Soc Trans. 1975;3(1):62-5. doi: 10.1042/bst0030062a.
5
Alkylation of intracellular and extracellular DNA by dimethylnitrosamine following activation by isolated rat hepatocytes.
Cancer Res. 1981 Sep;41(9 Pt 1):3471-4.
6
Removal of methylated purines from rat liver DNA after administration of dimethylnitrosamine.给予二甲基亚硝胺后大鼠肝脏DNA中甲基化嘌呤的去除
Cancer Res. 1978 Jul;38(7):2011-7.
7
The absorption and metabolism in rats of small oral doses of dimethylnitrosamine. Implication for the possible hazard of dimethylnitrosamine in human food.大鼠对小剂量口服二甲基亚硝胺的吸收与代谢。对二甲基亚硝胺在人类食物中可能存在的危害的启示。
Biochem J. 1977 Jun 15;164(3):497-500. doi: 10.1042/bj1640497.
8
Activation of a beta-hydroxyalkylnitrosamine to alkylating agents: evidence for the involvement of a sulfotransferase.
Cancer Res. 1992 Jun 15;52(12):3300-5.
9
Methylation of DNA guanine via the 1-carbon pool in dimethylnitrosamine-treated rats.
Mutat Res. 1986 Jan;173(1):73-9. doi: 10.1016/0165-7992(86)90014-x.
10
Hepatic microsomal metabolism of N-nitrosodimethylamine to its methylating agent.
Toxicol Appl Pharmacol. 1980 Jun 15;54(1):76-89. doi: 10.1016/0041-008x(80)90009-5.

引用本文的文献

1
PBPK model-based gender-specific risk assessment of N-nitrosodimethylamine (NDMA) using human biomonitoring data.基于 PBPK 模型的人体生物监测数据对 N-亚硝基二甲胺（NDMA）的性别特异性风险评估。
Arch Toxicol. 2024 Oct;98(10):3269-3288. doi: 10.1007/s00204-024-03828-w. Epub 2024 Aug 3.
2
Physiologically-based pharmacokinetic model for evaluating gender-specific exposures of N-nitrosodimethylamine (NDMA).用于评估 N-亚硝基二甲胺（NDMA）性别特异性暴露的基于生理学的药代动力学模型。
Arch Toxicol. 2024 Mar;98(3):821-835. doi: 10.1007/s00204-023-03652-8. Epub 2023 Dec 21.
3
Risk assessment of nitrosamines in food.
食品中亚硝胺的风险评估。
EFSA J. 2023 Mar 28;21(3):e07884. doi: 10.2903/j.efsa.2023.7884. eCollection 2023 Mar.
4
Potential anti-hepatocellular carcinoma properties and mechanisms of action of clerodane diterpenes isolated from Polyalthia longifolia seeds.从长叶远志种子中分离得到的 clerodane 二萜的潜在抗肝癌特性和作用机制。
Sci Rep. 2022 Jun 3;12(1):9267. doi: 10.1038/s41598-022-13383-y.
5
6-Carboxyfluorescein and structurally similar molecules inhibit DNA binding and repair by O⁶-alkylguanine DNA alkyltransferase.6-羧基荧光素和结构类似的分子通过 O⁶-烷基鸟嘌呤 DNA 烷基转移酶抑制 DNA 结合和修复。
DNA Repair (Amst). 2011 Dec 10;10(12):1193-202. doi: 10.1016/j.dnarep.2011.09.007. Epub 2011 Oct 5.
6
Removal of O6-methylguanine from DNA by human liver fractions.人肝脏组分对DNA中O6-甲基鸟嘌呤的去除作用。
Proc Natl Acad Sci U S A. 1982 Sep;79(17):5162-5. doi: 10.1073/pnas.79.17.5162.
7
Chemical and biochemical dosimetry of exposure to genotoxic chemicals.遗传毒性化学物质暴露的化学和生化剂量测定法。
Environ Health Perspect. 1985 Oct;62:5-18. doi: 10.1289/ehp.85625.
8
Modifying effects of disulfiram on DNA adduct formation and persistence of benzaldehyde in N-nitroso-N-methyl-benzylamine-induced carcinogenesis in rats.双硫仑对N-亚硝基-N-甲基苄胺诱导大鼠致癌过程中DNA加合物形成及苯甲醛持久性的修饰作用。
J Cancer Res Clin Oncol. 1986;112(2):75-80. doi: 10.1007/BF00404385.
9
The potential usefulness of biological markers in risk assessment.生物标志物在风险评估中的潜在用途。
Environ Health Perspect. 1987 Dec;76:141-5. doi: 10.1289/ehp.8776141.
10
Benzene adducts with rat nucleic acids and proteins: dose-response relationship after treatment in vivo.苯与大鼠核酸和蛋白质的加合物：体内处理后的剂量反应关系。
Environ Health Perspect. 1989 Jul;82:259-66. doi: 10.1289/ehp.8982259.