Cortinovis A, Crippa A, Bellorini R
Chir Ital. 1980 Oct;32(5):996-1005.
A group of patients with "cirrhosis of the liver", confirmed by biotic examination, were first subjected to radiographic examination of the coeliac tripod so as to confirm the presence of porto-hepatic or portocaval shunts; the blocked suprahepatic pressure and the porto-hepatic gradient were then determined. The porto-hepatic gradient values showed high variability, ranging from normal values (4 mm Hg) to values of 24 or more mm Hg, characteristic of portal hypertension of high severity. This is confirmation of the possibility that a cirrhosis, even though with presence of collateral circulations, need not necessarily be linked to a hemodynamic situation of portal hypertension. The observation, then, of normal portal pressure in the most advanced stages of cirrhosis (3rd stage according to the ALPERT and MITRA classification) seems to indicate the tendency to normalization of the portal pressure values in evolution of the disease.
一组经活检确诊为“肝硬化”的患者首先接受了腹腔动脉三叉的放射检查，以确认是否存在肝门静脉分流或门腔分流；然后测定肝上阻塞压和肝门静脉梯度。肝门静脉梯度值显示出高度变异性，范围从正常值（4毫米汞柱）到24毫米汞柱或更高的值，这是高严重程度门静脉高压的特征。这证实了即使存在侧支循环，肝硬化也不一定与门静脉高压的血流动力学情况相关的可能性。然后，在肝硬化最晚期阶段（根据阿尔珀特和米特拉分类为第3期）观察到正常门静脉压力，这似乎表明在疾病进展过程中门静脉压力值有趋于正常化的趋势。
