Sano K, Wakai S, Ochiai C, Takakura K
Childs Brain. 1981;8(2):98-106. doi: 10.1159/000119971.
18 cases of meningiomas in childhood below the age of 15 years at the onset of symptoms and signs were experienced in our clinic. They were studied as for the incidence, age and sex distributions, symptoms and signs at the onset, tumor locations, histological types, presence of cyst, dural attachments, and prognosis, in comparison with cases in adolescence (18 cases) and in adults (498 cases). Distinctive features in childhood meningiomas were: (1) relatively high incidence in the lateral ventricles (11.1%), (2) high incidence of cyst formation in the tumor (16.7%), and (3) of cases without any dural attachment (12.5%). These features were statistically significant as compared to adult cases (p less than 0.05). Features 1 and 2 were also true for adolescence cases. It was also revealed that male patients were predominant in childhood and adolescence (M:F = 10.8) in contrast to female predominance in adults (M:F = 1:1.6). The most frequent histological type was sarcomatous type (6 out of 18). It may be of interest that 3 cases of this malignant type have been alive for more than 10 years.
我院收治了18例15岁以下儿童期起病的脑膜瘤患者。对其发病率、年龄和性别分布、起病时的症状和体征、肿瘤位置、组织学类型、囊肿情况、硬膜附着情况及预后进行了研究，并与青少年组（18例）和成人组（498例）进行比较。儿童脑膜瘤的显著特征为：（1）侧脑室发病率相对较高（11.1%）；（2）肿瘤内囊肿形成发生率高（16.7%）；（3）无任何硬膜附着的病例占比（12.5%）。与成人病例相比，这些特征具有统计学意义（p<0.05）。特征1和2在青少年病例中也同样存在。还发现儿童期和青少年期男性患者居多（男:女 = 10.8），而成人以女性居多（男:女 = 1:1.6）。最常见的组织学类型为肉瘤型（18例中有6例）。值得注意的是，3例这种恶性类型的患者已存活超过10年。
