Fuller P W, Weber B A, Fujikawa S
Child Dev. 1981 Jun;52(2):749-51.
This study was conducted to determine whether an averaged evoked potential technique using a random-versus-repetitive presentation mode, could be used to study auditory discrimination in infants. We were interested in which stimulus mode, random-novel or repetitive, would result in greater responsiveness in terms of central nervous system evoked potential latencies and amplitudes. Recordings were made of 20 normal full-term infants between 14 and 18 weeks of age. Two different stimuli were used to create the random and repetitive modes: a burst of 125-Hz square waves (a buzz) and a burst of white noise. Two interstimulus intervals were also used, fast (1,000 msec) and slow (1,700 msec), to determine which rate is most effective. Ten of the infants were tested at the slow rate and 10 at the fast rate. Results for the N2 component of the averaged evoked potential (AEP) showed a main effect of presentation mode with a shorter latency for random versus repetitive. The shortest onset latency was for the random stimulus at the fast rate. The mean amplitude of N2 for all repetitive presentations at the slow rate was significantly larger.
本研究旨在确定一种采用随机与重复呈现模式的平均诱发电位技术是否可用于研究婴儿的听觉辨别能力。我们感兴趣的是，哪种刺激模式，即随机新颖模式还是重复模式，会在中枢神经系统诱发电位潜伏期和波幅方面产生更大的反应性。对20名14至18周龄的正常足月婴儿进行了记录。使用两种不同的刺激来创建随机和重复模式：一阵125赫兹的方波（嗡嗡声）和一阵白噪声。还使用了两种刺激间隔，快速（1000毫秒）和慢速（1700毫秒），以确定哪种速率最有效。10名婴儿以慢速进行测试，10名婴儿以快速进行测试。平均诱发电位（AEP）的N2成分结果显示，呈现模式有主要效应，随机模式的潜伏期比重复模式短。最短的起始潜伏期是快速率下的随机刺激。慢速下所有重复呈现的N2平均波幅明显更大。
