Bryant S G, Ereshefsky L
Drug Intell Clin Pharm. 1981 Jul-Aug;15(7-8):572-7. doi: 10.1177/1060028081015007-808.
The authors have investigated reasons for medication compliance in a population of epileptic patients. The hypothesis that the health care belief model would be predictive of medication-taking behavior was validated. A pilot study was constructed which investigated the comparative responses of compliant and noncompliant epileptic outpatients to questions regarding demographic, clinical history, and attitudinal characteristics. Noncompliant patients were characterized as having a longer duration of epilepsy, more complicated dosage regimens, and more changes in medication. In addition, noncompliant patients both demonstrated more confusion over medication directions and less insight into the need for anticonvulsants and feared addiction to their medication. They had a lower level of satisfaction with their health care and were more frequently subject to the social complications of epilepsy. The authors suggest that a more holistic approach be taken when attempting to reverse noncompliant behavior.
作者们调查了癫痫患者群体中药物依从性的原因。验证了医疗保健信念模型能够预测服药行为这一假设。开展了一项试点研究，调查了依从性和非依从性癫痫门诊患者对有关人口统计学、临床病史和态度特征问题的比较反应。非依从性患者的特点是癫痫病程更长、用药方案更复杂、用药变化更多。此外，非依从性患者对用药说明表现出更多困惑，对使用抗惊厥药物的必要性认识不足，且担心药物成瘾。他们对医疗保健的满意度较低，更频繁地遭受癫痫的社会并发症。作者们建议，在试图扭转不依从行为时应采取更全面的方法。
