Loiseau P, Marchal C
Clinique Neurologique, Université de Bordeaux, France.
Epilepsy Res Suppl. 1988;1:135-40.
A questionnaire was filled out by 270 epileptic outpatients responsible for taking their own medication to assess the extent of drug compliance-adherence and look for factors associated with poor compliance. Eighty-six patients (31.8%) were considered non-compliers. Significant factors for non-compliance were a duration of disease from 10 to 20 years, a low frequency of seizures and a drug intake considered as very bothersome. Neither sex nor age at onset, nor age at survey, nor type of epilepsy were different in compliers and non-compliers. Stopping medication to see if one is cured was more frequent in women than in men and a fear of drug toxicity was more frequent in patients over 30 years old.
270名负责自行服药的癫痫门诊患者填写了一份问卷,以评估药物依从性的程度,并寻找与依从性差相关的因素。86名患者(31.8%)被视为不依从者。不依从的显著因素包括病程为10至20年、癫痫发作频率低以及认为药物摄入非常麻烦。依从者和不依从者在性别、发病年龄、调查时年龄或癫痫类型方面均无差异。停药以查看是否治愈的情况在女性中比在男性中更常见,而对药物毒性的恐惧在30岁以上患者中更常见。