Ferrucci J T, Wittenberg J
Radiology. 1978 Dec;129(3):739-44. doi: 10.1148/129.3.739.
Computed tomographic guided fine needle aspiration biopsy of 25 consecutive patients with a variety of confirmed malignant abdominal and plevic neoplasms resulted in a 100% yield of positive tissue diagnosed, without significant complications. The principal advantage of CT guidance is the continuous direct observation of the needle tip position in relation to the target volume. Simultaneous insertion of 2 fine caliber biopsy needles (tandem needle maneuver) is a new technique developed for rapid, accurate needle repositioning for repeated aspiration attempts. CT guidance, multiple aspirates with the fine needle, and the tandem needle maneuver for precise localization all contribute to a high rate of tissue diagnoses. Because CT guidance permits more precise sampling of smaller, deeper tumors than other procedures, including ultrasonic biopsy transducer systems, it is preferred for percutaneous tissue sampling of abdominal neoplasms. Preliminary experience suggests that a large proportion of symptomatic abdominal malignancies which can be diagnosed by CT are amenable to successful percutaneous biopsy by this technique.
对25例经确诊患有各种腹部和盆腔恶性肿瘤的患者进行计算机断层扫描引导下的细针穿刺活检，组织诊断阳性率达100%，且无明显并发症。CT引导的主要优点是能持续直接观察针尖相对于目标体积的位置。同时插入2根细口径活检针（串联针操作）是一种为快速、准确地重新定位针以便进行重复抽吸尝试而开发的新技术。CT引导、细针多次抽吸以及用于精确定位的串联针操作都有助于提高组织诊断率。由于CT引导比其他方法（包括超声活检换能器系统）能更精确地对更小、更深的肿瘤进行采样，因此它更适合用于腹部肿瘤的经皮组织采样。初步经验表明，很大一部分可通过CT诊断的有症状腹部恶性肿瘤都适合用这种技术成功进行经皮活检。
