Roszkiewicz A, Roszkiewicz J, Zawistowski S
Gegenbaurs Morphol Jahrb. 1981;127(1):3-11.
Under hypercalcemia induced by calcium gluconate the degranulation of renomedullary interstitial cells accompanied with the increase in volume of the rough and smooth surfaced endoplasmic reticulum and enlargement of the Golgi apparatus were observed. The ultrastructural changes can be regarded as an expression of the increase of a synthetic and secretory activity of these cells. Because the changes of renomedullary cells observed in hypercalcemia induced by calcium gluconate are not really different from that observed in hypercalcemia induced by vitamin D3 (Roszkiewicz et al. 1979) it can suppose that these changes may be connected solely with a calcium serum elevation and that the renomedullary interstitial cells rather do not play any important role in vitamin D3 metabolism.
在葡萄糖酸钙诱导的高钙血症情况下，观察到肾髓质间质细胞脱颗粒，同时伴有粗面和滑面内质网体积增加以及高尔基体增大。这些超微结构变化可被视为这些细胞合成和分泌活性增强的表现。由于葡萄糖酸钙诱导的高钙血症中观察到的肾髓质细胞变化与维生素D3诱导的高钙血症中观察到的变化并无实际差异（罗斯基维茨等人，1979年），因此可以推测这些变化可能仅与血清钙升高有关，并且肾髓质间质细胞在维生素D3代谢中可能并不起重要作用。
