Transmission of hepatitis-B-virus by pleural effusion containing Dane particles.

Hepatitis-B-surface antigen HBSAG), hepatitis B-e antigen (HBe(HBeAG), and anti-HBc and Dane particles were demonstrated in pleural effusion obtained from an individual with a protracted course of an acute type B hepatitis, Pleural effusion was found to be unrelated to hepatitis-B-virus (HBV) infection. A physician who injured herself with a needle contaminated with pleural effusion experienced asymptomatic acute type B hepatitis.