Photoradiation therapy for cutaneous and subcutaneous malignancies.

Photoradiation therapy (PRT) using hematoporphyrin derivative (Hpd) as the photosensitizing agent is being developed for local treatment of a wide variety of malignant lesions including those involving the skin. The largest group of patients in this category are those with metastatic breast carcinoma in which 34/35 showed response to PRT. Other patients showing response to PRT are those with basal cell carcinoma, malignant melanoma, and squamous cell carcinoma.