Durkovský J, Michalíková B, Petrík P
Neoplasma. 1980;27(6):723-32.
An analysis was made of the results of irradiation therapy applied during the period 1965-1976 to 131 patients with Hodgkin's disease. The results of radiotherapy only of clinically positive lymphogranuloma localizations were compared with those of irradiation of both positive and negative nodes. The evaluation criteria used were the numbers of 3-year long primary remissions, 3-year long survival rates, frequency of onset and localization of relapses. Better therapeutic effects were achieved by radiotherapy as regards duration of primary remission, survival rate and frequency of relapses in originally clinically negative nodes proximate to positive nodes. However, the number of trans-diaphragmatic and extralymphatic relapses did not decline. A 5-year survival rate regardless of the irradiation method and clinical stage in 131 patients (1965-1974) was attained by 70.2%. The discussion bears on problems of an optimum radiotherapy and combined radiochemotherapy, and the significance of diagnostic laparotomy in lymphogranuloma.
对1965年至1976年间接受放射治疗的131例霍奇金病患者的治疗结果进行了分析。仅对临床上阳性的淋巴肉芽肿部位进行放射治疗的结果与对阳性和阴性淋巴结均进行照射的结果进行了比较。所使用的评估标准为3年长期初次缓解的数量、3年长期生存率、复发的发生率及部位。就初次缓解持续时间、生存率以及紧邻阳性淋巴结的原本临床上阴性的淋巴结复发频率而言，放射治疗取得了更好的治疗效果。然而，经横膈膜及淋巴外复发的数量并未下降。在131例患者（1965 - 1974年）中，无论采用何种照射方法及临床分期，5年生存率达到了70.2%。讨论涉及最佳放射治疗和联合放化疗的问题，以及诊断性剖腹术在淋巴肉芽肿中的意义。
