碘 - 125衰变对DNA的放射化学损伤范围。
Range of radiochemical damage to DNA with decay of iodine-125.
作者信息
Martin R F, Haseltine W A
出版信息
Science. 1981 Aug 21;213(4510):896-8. doi: 10.1126/science.7256283.
PMID:7256283
Abstract
Studies of the length of DNA fragments produced upon decay of iodine-125-labeled deoxycytidine that was located at a single position within a DNA fragment of defined sequence demonstrate that most radiochemical damage occurs within 15 to 20 angstroms of the site of iodine-125 decay. However, DNA strand breakage was detectable up to 70 angstroms from the site of iodine-125 decay.
摘要
对位于特定序列的DNA片段内单个位置的碘-125标记脱氧胞苷衰变时产生的DNA片段长度进行的研究表明，大多数放射化学损伤发生在碘-125衰变位点的15至20埃范围内。然而，在距碘-125衰变位点70埃处仍可检测到DNA链断裂。
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