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Single channel characteristics of some synthetic gramicidins.

作者信息

Tredgold R H, Hole P N, Sproule R C, Elgamal M

出版信息

Biochim Biophys Acta. 1977 Dec 1;471(2):189-94. doi: 10.1016/0005-2736(77)90249-8.

DOI:10.1016/0005-2736(77)90249-8
PMID:72563
Abstract

The synthesis of two new variants of gramicidin is described. It is shown that the changes in the aromatic side groups do not influence the single channel conductivity. Experiments in which solutions having different molarities on the two sides of the bilayer lipid membrane are described and their results compared with a rate theory analysis. It is concluded that the gramicidin pore contains approximately 10 equal potential maxima.

摘要

相似文献

1
Single channel characteristics of some synthetic gramicidins.
Biochim Biophys Acta. 1977 Dec 1;471(2):189-94. doi: 10.1016/0005-2736(77)90249-8.
2
Voltage-induced thickness changes of lipid bilayer membranes and the effect of an electrin field on gramicidin A channel formation.电压诱导的脂质双分子层膜厚度变化以及电场对短杆菌肽A通道形成的影响。
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Structure of the gramicidin A channel: discrimination between the piL,D and the beta helix by electrical measurements with lipid bilayer membranes.短杆菌肽A通道的结构:通过脂质双层膜的电学测量区分πL,D和β螺旋
Proc Natl Acad Sci U S A. 1977 Jun;74(6):2402-6. doi: 10.1073/pnas.74.6.2402.
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Correlation analysis of electrical noise in lipid bilayer membranes: kinetics of gramicidin A channels.脂质双分子层膜中电噪声的相关性分析:短杆菌肽A通道的动力学
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6
Channel formation kinetics of gramicidin A in lipid bilayer membranes.短杆菌肽A在脂质双分子层膜中的通道形成动力学。
J Membr Biol. 1973;11(2):177-94. doi: 10.1007/BF01869820.
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Single-channel studies on linear gramicidins with altered amino acid sequences. A comparison of phenylalanine, tryptophane, and tyrosine substitutions at positions 1 and 11.对氨基酸序列改变的线性短杆菌肽进行的单通道研究。对第1位和第11位苯丙氨酸、色氨酸和酪氨酸取代情况的比较。
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The action of a carbonsuboxide dimerized gramicidin A on lipid bilayer membranes.二聚化短杆菌肽A的二氧化碳对脂质双分子层膜的作用。
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Effects of surface charge on the conductance of the gramicidin channel.表面电荷对短杆菌肽通道电导的影响。
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N-acetyl gramicidin: single-channel properties and implications for channel structure.N-乙酰短杆菌肽:单通道特性及其对通道结构的影响
Science. 1979 Jan 5;203(4375):55-7. doi: 10.1126/science.83000.

引用本文的文献

1
Gramicidin A backbone and side chain dynamics evaluated by molecular dynamics simulations and nuclear magnetic resonance experiments. I: molecular dynamics simulations.通过分子动力学模拟和核磁共振实验评估格兰菌素 A 主链和侧链的动力学。I:分子动力学模拟。
J Phys Chem B. 2011 Jun 9;115(22):7417-26. doi: 10.1021/jp200904d. Epub 2011 May 16.
2
Single channels of 9, 11, 13, 15-destryptophyl-phenylalanyl-gramicidin A.9,11,13,15-去色氨酸-苯丙氨酰短杆菌肽A的单通道
Biophys J. 1982 Oct;40(1):87-9. doi: 10.1016/S0006-3495(82)84462-7.
3
On the potential variation in the gramicidin channel.
关于短杆菌肽通道中的电位变化
Biophys J. 1979 Feb;25(2 Pt 1):373-7. doi: 10.1016/s0006-3495(79)85299-6.