关于短杆菌肽通道中的电位变化
On the potential variation in the gramicidin channel.
作者信息
Tredgold R H
出版信息
Biophys J. 1979 Feb;25(2 Pt 1):373-7. doi: 10.1016/s0006-3495(79)85299-6.
Abstract
A simple model for the gramicidin ion pore is analyzed in which the potential energy of the ion in the pore can be resolved into three parts: a series of equal potential barriers, the contribution from the applied potential, and a parabolic variation leading to either a potential maximum or a potential minimum at the center of the membrane. For low ion concentrations, the particular case corresponding to a potential minima 2kT below the surface potential predicts experimentally observed behavior.
摘要
分析了一种简单的短杆菌肽离子通道模型，其中通道内离子的势能可分解为三部分：一系列等势垒、外加电势的贡献以及导致膜中心出现电势最大值或最小值的抛物线变化。对于低离子浓度，对应于比表面电势低2kT的电势最小值的特殊情况预测了实验观察到的行为。
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