Botey J, Martí E, Eseverri J L, Malet E, Zubizarreta A
Allergol Immunopathol (Madr). 1981 Jan-Feb;9(1):19-24.
In this study, we report the IgE, IgA, IgM and IgG levels in the serum and the secretory IgA obtained from a group of children of different ages with normal morphgram, with no personal or family history of allergies and without recurrent infectious diseases. The IgG, IgA and IgM and salivary secretory IgA were determined by the immunonephelometry technique, using specific anti-serum for heavy chains obtained form rabbits and purified by affinitive chromatography. The IgE was determined by radioimmunoassay, using the PRIST technique. If we look at all published works about normal levels of immunoglobulins in serum, we can see many differences among the results obtained by different authors. Our results are different as well; however, there is no difference in IgE levels. In our work, the secretory IgA level cannot be compared as we do not have any other study available for comparison. We think that our results differ from those obtained by other authors because of differences in laboratory and statistical techniques and other factors such as environment, constitution, nutrition, etc.
在本研究中，我们报告了一组不同年龄、形态正常、无个人或家族过敏史且无反复感染性疾病的儿童血清中的IgE、IgA、IgM和IgG水平，以及所获得的分泌型IgA水平。IgG、IgA、IgM和唾液分泌型IgA采用免疫比浊法测定，使用从兔获得并经亲和层析纯化的重链特异性抗血清。IgE采用放射免疫分析法，使用PRIST技术测定。如果查看所有已发表的关于血清中免疫球蛋白正常水平的研究，我们可以看到不同作者获得的结果存在许多差异。我们的结果也有所不同；然而，IgE水平没有差异。在我们的研究中，由于没有其他可供比较的研究，分泌型IgA水平无法进行比较。我们认为我们的结果与其他作者不同是因为实验室和统计技术的差异以及环境、体质、营养等其他因素。
