Geller-Bernstein C, Kenett R, Barsky T, Tsur S, Lahav M, Levin S
Pediatric Allergy and Pediatric Research Institute, Kaplan Hospital, Rehovot, Israel.
Ann Allergy. 1988 Oct;61(4):296-9.
IgA, IgG, IgM, and IgE levels in healthy, non-atopic, Israeli-born children aged 20 days to 16 years were analyzed and showed similar age-related values and dynamics as those of white populations found in other countries. No significant effect of sex of the individual or ethnic origin of the parents was found on the IgE values at different ages. This may indicate that total IgE levels are strongly influenced by environmental factors. Establishing tolerance limits at 97.5, 95, 75, 25 and 5th percentiles and the geometric mean provides the practitioner with more complete reference values. The use of multivariate control charts with tolerance limits from normal IgA, IgG, IgM, and IgE levels is described and is offered as an additional tool for the diagnosis of an allergic individual.
对20天至16岁健康、非特应性、在以色列出生的儿童的IgA、IgG、IgM和IgE水平进行了分析，结果显示其与其他国家白人人群的年龄相关值及动态变化相似。未发现个体性别或父母种族对不同年龄的IgE值有显著影响。这可能表明总IgE水平受环境因素的强烈影响。确定第97.5、95、75、25和第5百分位数的耐受限度以及几何平均值，可为从业者提供更完整的参考值。描述了使用具有来自正常IgA、IgG、IgM和IgE水平的耐受限度的多变量控制图，并将其作为诊断过敏个体的附加工具。
