Prescott R J, Jones D R, Vasilescu C, Henderson J T, Ruckley C V
Thromb Haemost. 1978 Aug 31;40(1):128-33.
The incidence of deep vein thrombosis (DVT) as diagnosed by the 125I fibrinogen test (125IFT) was determined in a series of 300 newly admitted medical and 201 surgical patients. 6 medical patients died before 125IFT screening could be completed. The incidence of DVT was 14% in medical patients and 18% in surgical patients. Increasing age, a malignant condition and a past history of thromboembolism all increased the risk of DVT. Increasing levels of cigarette smoking were found to be associated with a reduced incidence of DVT. Although statistical significance was achieved at only the 10% level for this finding it is in agreement with the results from studies on patients with myocardial infarction. The protective effect of cigarrette smoking was observed at all ages, and in both medical and surgical patients.
通过125I纤维蛋白原试验（125IFT）诊断的深静脉血栓形成（DVT）发生率，在300例新入院的内科患者和201例外科患者中进行了测定。6例内科患者在完成125IFT筛查前死亡。内科患者DVT发生率为14%，外科患者为18%。年龄增加、恶性疾病和既往血栓栓塞病史均增加DVT风险。发现吸烟量增加与DVT发生率降低相关。尽管这一发现仅在10%水平达到统计学显著性，但与心肌梗死患者的研究结果一致。在所有年龄段以及内科和外科患者中均观察到吸烟的保护作用。
