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梅毒血清学检测的诊断与随访(作者译)

[Diagnosis and follow-up of syphilis by serological tests (author's transl)].

作者信息

Piérard G E, Hermanns J F, Franchimont C, Damseaux M

出版信息

Ann Dermatol Venereol. 1980 Mar;107(3):121-6.

PMID:7258976
Abstract

Sensitivity and specificity of TPHA, TPI, RPCF, Kline's and Kolmer's tests are compared in a retrospective study carried out on 2,500 sera. The interest of these tests differs as far as diagnosis and survey of syphilis are concerned and the association of TPHA with a quantitative test as Kline's test appears optimal. TPHA is highly sensitive and specific. Its positivity, which usually remains after treatment, is particularly valuable in the diagnosis of cases of late syphilis. Its association with a quantitative test brings a better evaluation of the evolutivity of the disease.

摘要

在一项对2500份血清进行的回顾性研究中,比较了梅毒螺旋体血凝试验(TPHA)、梅毒螺旋体制动试验(TPI)、快速血浆反应素环状卡片试验(RPCF)、克莱恩试验(Kline's test)和柯尔默试验(Kolmer's test)的敏感性和特异性。就梅毒的诊断和监测而言,这些试验的意义各不相同,TPHA与如克莱恩试验这样的定量试验联合使用似乎最为理想。TPHA具有高度的敏感性和特异性。其阳性结果通常在治疗后仍会持续,这在晚期梅毒病例的诊断中尤为重要。它与定量试验联合使用能更好地评估疾病的发展情况。

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