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中脑丘脑系统持续自我刺激产生的成瘾样行为(作者译)

[Addiction-like behavior with continuous self-stimulation of the mediothalamic system (author's transl)].

作者信息

Schmidt B, Richter-Rau G, Thoden U

出版信息

Arch Psychiatr Nervenkr (1970). 1981;230(1):55-61. doi: 10.1007/BF00343767.

DOI:10.1007/BF00343767
PMID:7259484
Abstract

In a patient with postamputation pain a continuous self-stimulation of the mediothalamic system by a chronic deep brain electrode induced a change in behavior, similar to addiction. At the same time various psychological tests (HAWIE, Benton, Hooper-VOT and concentration tests) were significantly disturbed. After interruption of the deep brain stimulation all induced psychic abnormalities normalized within a few days.

摘要

在一名截肢后疼痛患者中,慢性深部脑电极对丘脑内侧系统的持续自我刺激导致了行为改变,类似于成瘾。与此同时,各种心理测试(HAWIE、本顿测试、胡珀 - VOT测试和注意力测试)受到显著干扰。在深部脑刺激中断后,所有诱发的精神异常在几天内恢复正常。

相似文献

1
[Addiction-like behavior with continuous self-stimulation of the mediothalamic system (author's transl)].中脑丘脑系统持续自我刺激产生的成瘾样行为(作者译)
Arch Psychiatr Nervenkr (1970). 1981;230(1):55-61. doi: 10.1007/BF00343767.
2
[Transformation of body scheme caused by thalamic stimulation. Thalamic stimulation for painful phantom limb (author's transl)].[丘脑刺激引起的身体图式改变。用于疼痛性幻肢的丘脑刺激(作者译)]
Neurochirurgie. 1981;27(2):121-3.
3
[Topography of stimulation sites with aversive effects in the rat's medial hypothalamus (author's transl)].[大鼠内侧下丘脑具有厌恶效应的刺激位点的地形图(作者译)]
J Physiol (Paris). 1975 Jul;70(2):201-6.
4
[Long-term results of transcutaneous neural stimulation in chronic neuralgia (author's transl)].
Nervenarzt. 1979 Mar;50(3):179-84.
5
Belief and relief of phantom-limb pain.幻肢痛的信念与缓解
Lancet. 1979 Nov 10;2(8150):1004.
6
Sensations evoked by stimulation in the midbrain of man.
J Neurosurg. 1969 Jan;30(1):14-24. doi: 10.3171/jns.1969.30.1.0014.
7
Sensory thalamus and periaqueductal grey area local field potential signals during bladder filling.感觉丘脑和导水管周围灰质区在膀胱充盈过程中的局部场电位信号。
J Clin Neurosci. 2019 Oct;68:342-343. doi: 10.1016/j.jocn.2019.07.037. Epub 2019 Jul 19.
8
[Stereotaxia in phantom-limb-neuralgia and causalgia (author's transl)].[幻肢神经痛和灼性神经痛中的立体定向术(作者译)]
Zentralbl Chir. 1979;104(15):989-93.
9
Letter: Dorsal column stimulation for phantom limb pain.信函:背柱刺激治疗幻肢痛
J Neurosurg. 1975 Aug;43(2):250-1. doi: 10.3171/jns.1975.43.2.0250.
10
Method of electrostimulation of the deep brain structures in treatment of some chronic diseases.在治疗某些慢性疾病中对深部脑结构进行电刺激的方法。
Confin Neurol. 1975;37(1-3):136-40. doi: 10.1159/000102727.

本文引用的文献

1
[Cerebral autostimulation in animal experiments; importance of experiments with autostimulation in neurophysiology and in cerebral localization of impulse mechanisms and of effects of drugs; parallels and differences in drug addiction behavior].[动物实验中的大脑自我刺激;神经生理学中自我刺激实验以及冲动机制的大脑定位和药物作用的重要性;药物成瘾行为中的异同]
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Positive reinforcement induced by intracerebral stimulation in the monkey.猴脑内刺激诱导的阳性强化。
J Comp Physiol Psychol. 1958 Feb;51(1):6-10. doi: 10.1037/h0048182.
3
Self-stimulation of the brain; its use to study local effects of hunger, sex, and drugs.
大脑的自我刺激;其用于研究饥饿、性和药物的局部效应。
Science. 1958 Feb 14;127(3294):315-24. doi: 10.1126/science.127.3294.315.
4
Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain.通过电刺激大鼠脑的隔区及其他区域产生的阳性强化。
J Comp Physiol Psychol. 1954 Dec;47(6):419-27. doi: 10.1037/h0058775.
5
Pain reduction in amputees by long-term spinal cord stimulation. Long-term follow-up study over 5 years.
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6
Relief of pain by electrical stimulation of the septal area.通过电刺激隔区缓解疼痛。
J Neurol Sci. 1967 Jul-Aug;5(1):115-20. doi: 10.1016/0022-510x(67)90012-3.
7
Striatal influence on facial pain.纹状体对面部疼痛的影响。
Confin Neurol. 1966;27(1):75-90. doi: 10.1159/000103936.
8
Naloxone reversal of analgesia produced by brain stimulation in the human.纳洛酮对人脑刺激所产生镇痛作用的逆转。
Pain. 1976 Jun;2(2):161-6.
9
Enkephalin-like material elevated in ventricular cerebrospinal fluid of pain patients after analgetic focal stimulation.镇痛性局部刺激后疼痛患者脑室脑脊液中脑啡肽样物质升高。
Science. 1978 Aug 4;201(4354):463-5. doi: 10.1126/science.663668.
10
Pain reduction by electrical brain stimulation in man. Part 1: Acute administration in periaqueductal and periventricular sites.人脑电刺激镇痛。第1部分:中脑导水管周围和脑室周围部位的急性给药
J Neurosurg. 1977 Aug;47(2):178-83. doi: 10.3171/jns.1977.47.2.0178.