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[高原低氧环境下大白鼠的心肌毛细血管情况]

[Myocardial capillarity of white rats during high-altitude hypoxia].

作者信息

Belkin V Sh

出版信息

Arkh Anat Gistol Embriol. 1981 Mar;80(3):48-52.

PMID:7259554
Abstract

In 128 mature white rats (males) after adaptation for 1--45 days, to 4,000 m altitude (North-West Pamir, Glasier Fortambek), weight characteristics of the heart were estimated (capillary diameters, their network density per 1 mm2 of the section summing length and volume in 1 mm3 of the right and left ventricular myocardium. Since the 21st day of the animals' staying at the altitute mentioned, a stable increase in the ventricular index occurs demonstrating a predominant right ventricular hyperfunction; the blood capillary volume in the left ventricular myocardium, during the whole time of the experiment, remains at the control levels, at the expense of the concomitant changes in the diameter and density. The blood capillary volume in the right ventricular myocardium, beginning from the first day of the experiment, increase essentially; this increase was kept up to the 14th day of the experiment, but, nevertheless, it remains at the control levels, at the expense of the concomitant changes in the diameter and density. The blood capillary volume in the right ventricular myocardium, beginning from the first day of the experiment, increase essentially; this increase was kept up to the 14th day of the experiment, but, nevertheless, it remains at the control levels, at the expense of the concomitant changes in the diameter and density. The blood capillary volume in the right ventricular myocardium, beginning from the first day of the experiment, increase essentially; this increase was kept up to the 14th day of the experiment, but, nevertheless, it did not exceed the volume indices of the left ventricular capillaries.

摘要

在128只成熟雄性白鼠适应海拔4000米(西北帕米尔,格拉西尔福尔坦贝克)1至45天后,对其心脏的重量特征进行了评估(毛细血管直径、每平方毫米切片的毛细血管网络密度、左右心室心肌每立方毫米的总和长度与体积)。自动物在上述海拔停留第21天起,心室指数持续稳定增加,表明右心室功能亢进占主导;在整个实验期间,左心室心肌中的毛细血管体积保持在对照水平,这是由直径和密度的相应变化所致。右心室心肌中的毛细血管体积从实验第一天起显著增加;这种增加持续到实验第14天,但仍保持在对照水平,这也是由直径和密度的相应变化所致。右心室心肌中的毛细血管体积从实验第一天起显著增加;这种增加持续到实验第14天,但仍保持在对照水平,这也是由直径和密度的相应变化所致。右心室心肌中的毛细血管体积从实验第一天起显著增加;这种增加持续到实验第14天,但仍未超过左心室毛细血管的体积指数。

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