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线粒体外膜的结构:来自植物膜的X射线衍射分析

Structure of the outer mitochondrial membrane: analysis of X-ray diffraction from the plant membrane.

作者信息

Mannella C A

出版信息

Biochim Biophys Acta. 1981 Jul 6;645(1):33-40. doi: 10.1016/0005-2736(81)90508-3.

DOI:10.1016/0005-2736(81)90508-3
PMID:7260085
Abstract

X-ray diffraction from centrifugally oriented specimens of plant outer mitochondrial membranes suggests that these membrane contain prominent in-plane subunits. The short lamellar repeat which these specimens display (as low as 5.1 nm) points to a predominantly internal localization of the protein components of these membranes. The simplest model for the putative in-plane subunit consistent with autocorrelation analysis of the normal-indicence diffraction data consists of two concentric rings of electron density with diameters of (approx.) 2 and 4 nm. These rings could represent the planar projections of concentric cylindrical shells, aligned normal to the membrane surface.

摘要

对植物线粒体外膜离心定向标本进行的X射线衍射表明,这些膜含有显著的面内亚基。这些标本显示出的短层状重复间距(低至5.1纳米)表明这些膜的蛋白质成分主要位于内部。与正常入射角衍射数据的自相关分析一致的假定面内亚基的最简单模型由两个直径约为2纳米和4纳米的同心电子密度环组成。这些环可能代表垂直于膜表面排列的同心圆柱壳的平面投影。

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