抗血友病因子（AHF）浓缩物中凝血因子 VIII 的促凝活性和抗原含量。
Factor VIII procoagulant and antigen content of antihemophilic factor (AHF) concentrates.
作者信息
Yang H C, Duffy C
出版信息
Transfusion. 1978 Nov-Dec;18(6):747-9. doi: 10.1046/j.1537-2995.1978.18679077961.x.
Abstract
Antihemophilic factor concentrates from six manufacturers were studied for factor VIII procoagulant and antigen content. Marked lot-to-lot differences were found in the factor VIII antigen:procoagulant ratio. The average antigen content was 2.33 times that of procoagulant activity in 21 lots studied, indicating a significant loss of activity during the fractionation process.
摘要
对来自六个生产商的抗血友病因子浓缩物进行了凝血因子 VIII 促凝剂和抗原含量研究。发现不同批次的凝血因子 VIII 抗原与促凝剂比例存在显著差异。在所研究的 21 个批次中，平均抗原含量是促凝活性的 2.33 倍，这表明在分级分离过程中活性有显著损失。
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