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[不同种类恒河猴细胞中的自发染色体重排]

[Spontaneous chromosome rearrangements in different kinds of rhesus monkey cells].

作者信息

Kosichenko L P

出版信息

Biull Eksp Biol Med. 1981 May;91(5):600-2.

PMID:7260392
Abstract

Spontaneous chromosome reconstructions were examined in bone marrow cells, peripheral blood lymphocytes and epithelial kidney cells from monkeys (Macaca mulatta). In normal monkeys, the chromosome reconstruction frequency was higher in epithelial kidney cells and lower in bone marrow cells. Peripheral blood lymphocytes occupied an intermediate position as regards the chromosome reconstruction frequency. The structural chromosome mutations were characterized mainly by single and twin fragments, with the former ones being predominant. The monkeys examined showed age-associated differences in the frequency of spontaneous chromosome reconstructions.

摘要

对猕猴(恒河猴)的骨髓细胞、外周血淋巴细胞和肾上皮细胞中的自发染色体重建进行了检测。在正常猕猴中,肾上皮细胞的染色体重建频率较高,而骨髓细胞中的频率较低。外周血淋巴细胞的染色体重建频率处于中间位置。染色体结构突变主要表现为单个和双个片段,其中单个片段更为常见。所检测的猕猴在自发染色体重建频率上呈现出与年龄相关的差异。

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