Korvin-Pavlovskaia E G, Karalova E M, Kul'minskaia A S, Magakian Iu A, Gazarian K G
Tsitologiia. 1978 Sep;20(9):1016-26.
Two types of biosynthetic processes associated with cytodifferentiation underlie the "reserve" erythropoiesis of pigeons during anemia: 1) cells rapidly increase their nuclear DNA amount up to the level of 4c, whereas the total protein remains at the initial level; furtheron, cells double also their protein amount, and then enter into the phase of differentiation and specialization; after having hemoglobin accumulation they divide; 2) a limited increase of DNA amount takes place up to the level not exceeding 130% of the initial level; in this case a synchronous increase of the hemoglobin amount is detected in the cell. The first type processes provide the accumulation of the specific product and the accelerated increase of the number of erythrocytes in the population. The second way is aimed only to the accumulation of the specific product in a greater amount.
与细胞分化相关的两种生物合成过程是贫血期间鸽子“储备”红细胞生成的基础:1)细胞迅速将其核DNA量增加到4c水平,而总蛋白保持在初始水平;随后,细胞的蛋白量也翻倍,然后进入分化和特化阶段;在积累血红蛋白后它们进行分裂;2)DNA量有限增加,达到不超过初始水平130%的水平;在这种情况下,细胞中检测到血红蛋白量同步增加。第一种类型的过程提供了特定产物的积累以及群体中红细胞数量的加速增加。第二种方式仅旨在大量积累特定产物。