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[雌性家兔孕期子宫肌层细胞质蛋白的组成及酶活性]

[Composition and enzymic activity of cytoplasmic proteins in myometrium of female rabbits during pregnancy].

作者信息

Nikolaeva E N

出版信息

Ukr Biokhim Zh (1978). 1978 Sep-Oct;50(5):570-2.

PMID:726091
Abstract

It is shown that on the 27-30th day of pregnancy in the myometrium cytoplasm of female rabbits the content of proteins, the aldolase (EC 4.1.2.7) and lactate dehydrogenase (EC 1.1.1.27) activities are increased. Redistribution between fractions of certain lactate dehydrogenase (LDH) isoenzymes is observed: the fraction of LDH4--5 increases and that of LDH1--2 decreases, and the ATPase (EC 3.6.1.3) activity lowers as well. A rise in the amount of proteins in the female rabbits myometrium cytoplasm in the last days of pregnancy and the growing fraction of LDH4--5 testify to the myometrium enchanced contractility during the labour.

摘要

结果表明,在雌性家兔怀孕第27 - 30天时,其子宫肌层细胞质中的蛋白质含量、醛缩酶(EC 4.1.2.7)和乳酸脱氢酶(EC 1.1.1.27)活性均增加。观察到某些乳酸脱氢酶(LDH)同工酶各组分之间发生了重新分布:LDH4 - 5组分增加,LDH1 - 2组分减少,同时ATP酶(EC 3.6.1.3)活性也降低。怀孕后期雌性家兔子宫肌层细胞质中蛋白质含量的增加以及LDH4 - 5组分的增多,证明分娩期间子宫肌层收缩力增强。

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