Morlans J A, Alvarez J, Dorticós F
Cor Vasa. 1981;23(3):233-7.
Hydrocortisone sodium succinate (HSS) (50 mg/1) was tested as a protective agent against the effects of hypoxia on rabbit papillary muscle fibres. No effect of HSS was observed on the electrophysiological variables studied in aerobic condition. Hypoxia (65-75 mmHg, 8.66-10.0 kPa) had no effects on the resting potential, amplitude and overshoot, and shortened the action potential at 0 and -60 mV levels of repolarization. In the presence of HSS the resting potential, amplitude and overshoot were also unaffected by the hypoxic condition. However, when measured at -60 mV level the changes on the repolarization phase after 15 and 60 minutes of hypoxia were significantly reduced, 14% and 24% respectively (p less than 0.001) as compared with the values obtained in the series without HSS.
对琥珀酸钠氢化可的松（HSS）（50毫克/1）作为抗缺氧对兔乳头肌纤维影响的保护剂进行了测试。在有氧条件下，未观察到HSS对所研究的电生理变量有影响。缺氧（65 - 75毫米汞柱，8.66 - 10.0千帕）对静息电位、振幅和超射无影响，并缩短了复极化0和 - 60毫伏水平的动作电位。在有HSS存在的情况下，静息电位、振幅和超射也不受缺氧条件的影响。然而，在 - 60毫伏水平测量时，与无HSS系列中获得的值相比，缺氧15分钟和60分钟后复极化阶段的变化分别显著降低了14%和24%（p小于0.001）。
