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Effects of palytoxin on the electrical activity of dog and rabbit heart.

作者信息

Weidmann S

出版信息

Experientia. 1977 Nov 15;33(11):1487-9. doi: 10.1007/BF01918825.

DOI:10.1007/BF01918825
PMID:21804
Abstract

Reversible effects of palytoxin, extracted from colonies of the soft coral Palythoa caribaeorum, are described. There is a decrease of both membrane resting potential and overshoot during activity. Rise time of the action potential is prolonged, while repolarization is shortened. The electrical events resemble those seen with metabolic poisons.

摘要

相似文献

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引用本文的文献

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Toxic potential of palytoxin.岩沙海葵毒素的潜在毒性。
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2
Palytoxin-induced effects on partial reactions of the Na,K-ATPase.刺尾鱼毒素对钠钾ATP酶部分反应的影响。
J Gen Physiol. 2006 Jul;128(1):103-18. doi: 10.1085/jgp.200609505.
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Large diameter of palytoxin-induced Na/K pump channels and modulation of palytoxin interaction by Na/K pump ligands.刺尾鱼毒素诱导的钠/钾泵通道的大直径以及钠/钾泵配体对刺尾鱼毒素相互作用的调节

本文引用的文献

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The plateau of the action potential of the frog ventricle.青蛙心室动作电位的平台期。
Circ Res. 1960 Jan;8:47-56. doi: 10.1161/01.res.8.1.47.
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Mol Pharmacol. 1977 Jan;13(1):181-4.