Kuemmerle H P
Int J Clin Pharmacol Ther Toxicol. 1981 Jul;19(7):289-96.
The clinical pharmacology of lipid-lowering agents and their meaning in the treatment of the fat metabolism-atherosclerosis functional circle are described. All the aspects associated with these important problems are carefully analyzed and the possible consequences for their rational use are interpreted. The current view of the actual situation in this field is presented and the trends in the development of prophylactic and therapeutic treatment with lipid-lowering agents in the fat metabolism-atherosclerosis functional circle are shown. Epidemiologic considerations complement these reflections.
本文描述了降脂药物的临床药理学及其在脂肪代谢-动脉粥样硬化功能循环治疗中的意义。仔细分析了与这些重要问题相关的所有方面,并解释了合理使用它们可能产生的后果。介绍了该领域当前的实际情况,并展示了在脂肪代谢-动脉粥样硬化功能循环中使用降脂药物进行预防和治疗的发展趋势。流行病学的考量补充了这些思考。