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恒河猴心率和血压的经典条件反射

Classical conditioning of heart rate and blood pressure in Macaca mulatta.

作者信息

Kadden R M, Schoenfeld W N, McCullough M R, Steele W A, Tremont P J

出版信息

J Auton Nerv Syst. 1980 Jul;2(2):131-42. doi: 10.1016/0165-1838(80)90041-7.

DOI:10.1016/0165-1838(80)90041-7
PMID:7264187
Abstract

Classical delay conditioning of heart rate, and of systolic and diastolic blood pressures, was carried out in 16 rhesus monkeys. Blood pressure and inter-systolic interval were measured from an in-dwelling arterial catheter; recordings were taken prior to conditioned stimulus (CS) on each trial, during a 20 sec visual stimulus that filled the conditioned-unconditioned stimulus (CS-UCS) interval, and following UCS (a brief electric tail-shock). The heart rate response both to CS and to UCS was biphasic (acceleration followed by deceleration); the blood pressure response functions were more complex, and were different for the CS and post-UCS periods. Comparison of the patterns of cardiac and blood pressure responses on any trial indicates a possible sequence of baroreceptor reflex activity.

摘要

对16只恒河猴进行了心率、收缩压和舒张压的经典延迟条件反射实验。通过留置动脉导管测量血压和收缩间期;在每次试验中,在条件刺激(CS)之前、在持续20秒的视觉刺激(该刺激填充了条件刺激-非条件刺激(CS-UCS)间隔)期间以及非条件刺激(短暂的电尾击)之后进行记录。对CS和UCS的心率反应均为双相性(先加速后减速);血压反应功能更为复杂,且在CS期和非条件刺激后时期有所不同。在任何一次试验中对心脏和血压反应模式的比较表明了压力感受器反射活动的一种可能顺序。

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Classical conditioning of heart rate and blood pressure in Macaca mulatta.恒河猴心率和血压的经典条件反射
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Effects of pharmacological autonomic blockade upon cardiac rate and blood pressure conditioned and unconditioned responses in Macaca mulatta.
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