Gelpi A P
West J Med. 1978 Nov;129(5):369-73.
Of 52 student patients with chronic inflammatory bowel disease who were observed at Stanford University over a three-year period, 16 had Crohn disease, 17 had ulcerative colitis and 19 had ulcerative proctitis. Patients with ulcerative colitis had relatively few complications. During the study period, only two students from the entire group of 52 were obliged to interrupt college attendance because of bowel disease or complications. Of the patients, 33 were first observed on remission or attained remission during the three-year observation period. Incidence and prevalence rates for Crohn disease and ulcerative colitis were comparable with age-specific rates from other published studies. At Stanford, the high reported frequency of proctitis, which exceeded that of proximal ulcerative colitis, was possibly a reflection of the diagnostic zeal with which patients with rectal bleeding were evaluated at the student health service.
在斯坦福大学三年期间观察的52例患有慢性炎症性肠病的学生患者中,16例患有克罗恩病,17例患有溃疡性结肠炎,19例患有溃疡性直肠炎。溃疡性结肠炎患者的并发症相对较少。在研究期间,52名学生中只有两名因肠道疾病或并发症而不得不中断大学学业。在这些患者中,33例在三年观察期内首次被观察到处于缓解期或达到缓解。克罗恩病和溃疡性结肠炎的发病率和患病率与其他已发表研究中的年龄特异性发病率相当。在斯坦福大学,报告的直肠炎高发病率超过了近端溃疡性结肠炎,这可能反映了学生健康服务中心对直肠出血患者进行评估时的诊断热情。