Gottrand F, Colombel J F, Moreno L, Salomez J L, Farriaux J P, Cortot A
Service de Pédiatrie, Gastroentérologie Pédiatrique et Génétique Médicale, Hôpital Huriez, Lille.
Arch Fr Pediatr. 1991 Jan;48(1):25-8.
The incidence of inflammatory bowel disease (IBD) in French children is not known. Therefore we conducted a prospective epidemiologic study of IBD in the region Nord-Pas-de-Calais (3.9 millions inhabitants). During the first 17 months of the study each new suspected case was reported by all (private and public) gastroenterologists in the region (n = 104) and a questionnaire was filled up at the gastroenterologist office by an epidemiologist. The final diagnosis of Crohn's disease (CD), ulcerative colitis (UC) or proctitis was made in a blind manner by two expert gastroenterologists. During the period under study, 47 new cases of IBD were registered in children (less than 17 years of age); 31 (66%) had CD, 7 (15%) had UC, and 9 (19%) had unclassified colitis. The incidence was 2.07/100,000 children/year for CD and 0.46/100,000 children/year for UC. These preliminary data suggest that the incidence of CD is high in Northern France.
法国儿童炎症性肠病(IBD)的发病率尚不清楚。因此,我们对北部加来海峡地区(390万居民)的IBD进行了一项前瞻性流行病学研究。在研究的前17个月里,该地区所有(私立和公立)胃肠病学家(共104人)报告了每一例新的疑似病例,一名流行病学家在胃肠病学家办公室填写了一份调查问卷。两名专家胃肠病学家以盲法对克罗恩病(CD)、溃疡性结肠炎(UC)或直肠炎做出最终诊断。在研究期间,儿童(17岁以下)中登记了47例新的IBD病例;31例(66%)患有CD,7例(15%)患有UC,9例(19%)患有未分类的结肠炎。CD的发病率为每年2.07/10万儿童,UC的发病率为每年0.46/10万儿童。这些初步数据表明,法国北部CD的发病率较高。