Huhmann W, Simon R, Lichtlen P
Z Kardiol. 1978 Nov;67(11):749-58.
Hemodynamic studies in pts. with Starr-Edwards disc valves (SE), Lillehei-Kaster valves (LK) and normal mitral valves (N) were performed to compare pressure gradient (deltaP) and volume flow (V). Therefore, synchronous pressure-volume measurements at a diastolic filling time of 500 ms and 250 ms were done. The results show that deltaP in SE valves is much higher than in LK-valves, but this exists only at the beginning of volume acceleration whereas at the end of diastolic time deltaP is similar to that of LK valves. In normal mitral valves initial pressure gradients are also present. Maximum volume flow in SE valves occurs at the end of diastole, but in normal mitral valves and in LK valves, however, it is reached already at the beginning. The studies showed a substantial obstacle to volume flow in SE-disc valves while LK-valves are similar to normal mitral valves.
对植入斯塔尔-爱德华兹碟瓣（SE）、 Lillehei-Kaster瓣（LK）以及正常二尖瓣（N）的患者进行血流动力学研究，以比较压力阶差（deltaP）和容积流量（V）。因此，在舒张期充盈时间为500毫秒和250毫秒时进行了同步压力-容积测量。结果显示，SE瓣中的deltaP远高于LK瓣，但这仅存在于容积加速开始时，而在舒张期末期，deltaP与LK瓣相似。正常二尖瓣中也存在初始压力阶差。SE瓣中的最大容积流量出现在舒张期末期，但在正常二尖瓣和LK瓣中，最大容积流量在舒张期开始时就已达到。研究表明，SE碟瓣对容积流量存在实质性阻碍，而LK瓣与正常二尖瓣相似。
