Karch D, Kindermann E, Arnold G
Klin Padiatr. 1981 Jul;193(4):301-4. doi: 10.1055/s-2008-1034480.
92 infants were studied in order to determine the prognostic value of bioelectric brain maturity assessment during newborn period. Psychomotor development was followed up until infants were at least one year old. Infants with abnormal follow-up examination findings showed a statistically significant retardation of "EEG-maturity" in comparison with infants who developed normally. The more unfavourable the psychomotor development was, the more immature was the EEG-pattern. The prognosis of 6 infants whose "EEG-maturity" was extremely retarded (= 4 weeks immature) was severe; their follow-up examination revealed either definite pathological findings or severe cerebral damage. All newborns whose abnormal electroencephalogram recording did not allow assessment of "EEG-maturity" developed severe cerebral damage. Comparing the prognostic value of risk factors with the bioelectric brain maturity the last method proved to be more valuable. Especially in infants with perinatal hypoxia this method showed the highest prognostic value.
为了确定新生儿期脑生物电成熟度评估的预后价值,对92名婴儿进行了研究。对婴儿的精神运动发育进行随访,直至婴儿至少1岁。随访检查结果异常的婴儿与正常发育的婴儿相比,在“脑电图成熟度”方面存在统计学上的显著延迟。精神运动发育越不利,脑电图模式就越不成熟。6名“脑电图成熟度”极度延迟(即不成熟4周)的婴儿预后严重;他们的随访检查显示有明确的病理发现或严重的脑损伤。所有脑电图记录异常而无法评估“脑电图成熟度”的新生儿都发生了严重的脑损伤。将风险因素的预后价值与脑生物电成熟度进行比较,结果证明后一种方法更有价值。特别是在围产期缺氧的婴儿中,这种方法显示出最高的预后价值。