Peradze T, Friedman E, Bitchurina M
Med Biol. 1981 Feb;59(1):41-6.
The characteristics of laboratory parameters of inactivated whole influenza virus vaccine, obtained by the purification of allantoic virus cultures on macroporous glass, are presented. The vaccine is characterized by small reactogenicity and safety, which allows it to be used in both adolescents and adults. Seroconversions to hemagglutinin have been found in 80--95% of individuals vaccinated once during the test vaccination by the preparation containing various strains of influenza A/H3N2/virus. Post-vaccination antibody rise has been investigated in the nasal secretion of vaccinated individuals.
介绍了通过在大孔玻璃上纯化尿囊病毒培养物获得的灭活全流感病毒疫苗的实验室参数特征。该疫苗的特点是反应原性小且安全性高，这使得它可用于青少年和成年人。在使用含有各种甲型H3N2病毒株的制剂进行试验性接种期间，80%至95%的单次接种个体出现了针对血凝素的血清转化。已对接种个体鼻分泌物中的疫苗接种后抗体升高情况进行了研究。
