Inactivated chromatographic influenza vaccine.

The characteristics of laboratory parameters of inactivated whole influenza virus vaccine, obtained by the purification of allantoic virus cultures on macroporous glass, are presented. The vaccine is characterized by small reactogenicity and safety, which allows it to be used in both adolescents and adults. Seroconversions to hemagglutinin have been found in 80--95% of individuals vaccinated once during the test vaccination by the preparation containing various strains of influenza A/H3N2/virus. Post-vaccination antibody rise has been investigated in the nasal secretion of vaccinated individuals.