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57钴-博来霉素作为原发性肝细胞癌的肿瘤扫描剂

57-cobalt-bleomycin as a tumor scanning agent in primary hepatocellular cancer.

作者信息

Kew M, Allen J, Levin J

出版信息

Eur J Nucl Med. 1976 Dec 30;1(4):247-50. doi: 10.1007/BF00252171.

Abstract

57Co-bleomycin and 99mTc-sulfur colloid scans were performed in 13 southern African black patients with primary hepatocellular cancer (PHC) and 3 patients with other space-occupying hepatic lesions. Selective concentration of 57Co-bleomycin in the defect or defects seen on the 99mTc-sulfur colloid scan occurred in only 4 of the 13 (31%) patients with PHC. In the remaining PHC patients, as well as in the 2 patients with metastatic liver disease and the 1 patient with an amebic liver abscess, the 57 Co-bleomycin and 99mTc-sulfur colloid scans were identical. 57Co-bleomycin appears to have only a limited place as a tumor-seeking agent in the diagnosis of PHC in southern African blacks.

摘要

对13例南非黑人原发性肝细胞癌(PHC)患者和3例其他肝脏占位性病变患者进行了57钴-博来霉素和99m锝-硫胶体扫描。在13例PHC患者中,只有4例(31%)在99m锝-硫胶体扫描所见的缺损部位出现了57钴-博来霉素的选择性浓聚。在其余的PHC患者以及2例转移性肝病患者和1例阿米巴肝脓肿患者中,57钴-博来霉素和99m锝-硫胶体扫描结果相同。在南非黑人PHC的诊断中,57钴-博来霉素作为一种肿瘤寻踪剂似乎只有有限的应用价值。

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