• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

他莫昔芬对乳腺癌患者阴道上皮的雌激素样作用。

Estrogen-like action of tamoxifen on vaginal epithelium in breast cancer patients.

作者信息

Boccardo F, Bruzzi P, Rubagotti A, Nicolò G U, Rosso R

出版信息

Oncology. 1981;38(5):281-5. doi: 10.1159/000225571.

DOI:10.1159/000225571
PMID:7266969
Abstract

The action of prolonged administration of Tamoxifen on the vaginal epithelium in postmenopausal breast cancer patients has been investigated by means of exfoliative cytology. Our study gives quite convincing evidence of a clear-cut estrogenic effect of Tamoxifen on vaginal epithelium. The relationship between estrogenic properties of Tamoxifen and breast cancer management is discussed.

摘要

通过脱落细胞学方法，研究了他莫昔芬长期给药对绝经后乳腺癌患者阴道上皮的作用。我们的研究提供了相当有说服力的证据，证明他莫昔芬对阴道上皮有明确的雌激素样作用。并讨论了他莫昔芬的雌激素特性与乳腺癌治疗之间的关系。

相似文献

1
Estrogen-like action of tamoxifen on vaginal epithelium in breast cancer patients.他莫昔芬对乳腺癌患者阴道上皮的雌激素样作用。
Oncology. 1981;38(5):281-5. doi: 10.1159/000225571.
2
Maturation of vaginal and endometrial epithelium in postmenopausal breast cancer patients receiving long-term tamoxifen.接受长期他莫昔芬治疗的绝经后乳腺癌患者阴道和子宫内膜上皮的成熟情况。
Gynecol Oncol. 1994 Dec;55(3 Pt 1):410-4. doi: 10.1006/gyno.1994.1314.
3
The effects of tamoxifen on the vaginal epithelium in postmenopausal women.
J Womens Health Gend Based Med. 2000 Jun;9(5):559-63. doi: 10.1089/15246090050073648.
4
Oestrogen-like effect of tamoxifen on vaginal epithelium.他莫昔芬对阴道上皮的雌激素样作用。
Br Med J. 1977 May 21;1(6072):1351-2. doi: 10.1136/bmj.1.6072.1351-e.
5
The influence of tamoxifen on the maturation index of vaginal epithelium.
Clin Exp Obstet Gynecol. 1998;25(4):121-4.
6
Estrogenic effects of toremifene and tamoxifen in postmenopausal breast cancer patients.托瑞米芬和他莫昔芬对绝经后乳腺癌患者的雌激素样作用。
Breast Cancer Res Treat. 2003 Nov;82(2):103-11. doi: 10.1023/B:BREA.0000003957.54851.11.
7
Comparison between the effects of tamoxifen and toremifene on the uterus in postmenopausal breast cancer patients.他莫昔芬与托瑞米芬对绝经后乳腺癌患者子宫影响的比较。
Gynecol Oncol. 1995 Nov;59(2):261-6. doi: 10.1006/gyno.1995.0019.
8
[Effects of long-term administration of tamoxifen on vaginal epithelium and complications of endometrial lesions in breast cancer patients].[长期服用他莫昔芬对乳腺癌患者阴道上皮及子宫内膜病变并发症的影响]
Nihon Sanka Fujinka Gakkai Zasshi. 1995 Feb;47(2):125-32.
9
Tamoxifen and proliferation of vaginal and cervical epithelium in postmenopausal women with breast cancer.他莫昔芬与绝经后乳腺癌女性阴道和宫颈上皮细胞增殖
Eur J Obstet Gynecol Reprod Biol. 1998 Oct;80(2):221-5. doi: 10.1016/s0301-2115(98)00117-1.
10
[Effect of tamoxifen and estrogens on breast cancer cell lines: MCF-7 and R-27, and on the uterus and vagina of fetal and newborn guinea-pigs].
Pathol Biol (Paris). 1985 Dec;33(10):987-92.

引用本文的文献

1
Challenges of Managing Lower Urinary Tract Symptoms in Women with Tamoxifen Use.他莫昔芬治疗的女性下尿路症状管理面临的挑战。
Womens Health Rep (New Rochelle). 2022 Apr 11;3(1):430-436. doi: 10.1089/whr.2021.0147. eCollection 2022.
2
Endometrial evaluation by ultrasonography, hysteroscopy and histopathology in cases of breast carcinoma on Tamoxifen therapy.他莫昔芬治疗乳腺癌患者时子宫内膜的超声、宫腔镜及组织病理学评估
J Midlife Health. 2015 Apr-Jun;6(2):59-65. doi: 10.4103/0976-7800.158947.
3
The effect of tamoxifen on the genital tract.
他莫昔芬对生殖道的影响。
Cancer Imaging. 2008 Jun 30;8(1):135-45. doi: 10.1102/1470-7330.2008.0020.
4
Letrozole as upfront endocrine therapy for postmenopausal women with hormone-sensitive breast cancer: BIG 1-98.来曲唑作为绝经后激素敏感性乳腺癌女性的一线内分泌治疗：BIG 1-98研究
Breast Cancer Res Treat. 2007;105 Suppl 1(Suppl 1):55-66. doi: 10.1007/s10549-007-9700-y. Epub 2007 Oct 3.
5
Suppression of Estrogenic Activity by Medroxyprogesterone Acetate in Tamoxifen-treated Patients after Surgery for Breast Cancer to Reduce the Risk of Endometrial Cancer Development.
Breast Cancer. 1996 Mar 29;3(1):25-31. doi: 10.1007/BF02966959.
6
Gynecologic effects of tamoxifen: case reports and review of the literature.他莫昔芬的妇科效应：病例报告及文献综述
Int Urogynecol J Pelvic Floor Dysfunct. 1996;7(4):179-84. doi: 10.1007/BF01907069.
7
Gynaecological effects of tamoxifen.他莫昔芬的妇科效应
J Clin Pathol. 1999 Feb;52(2):83-8. doi: 10.1136/jcp.52.2.83.
8
The influence of antiestrogens on the release of plasminogen activator (uPA) by MDA-MB-231 and MCF-7 breast cancer cells.抗雌激素对MDA-MB-231和MCF-7乳腺癌细胞纤溶酶原激活物（uPA）释放的影响。
Clin Exp Metastasis. 1998 Apr;16(3):235-41. doi: 10.1023/a:1006592809040.
9
Differential influence of antiestrogens on the in vitro release of gelatinases (type IV collagenases) by invasive and non-invasive breast cancer cells.抗雌激素对侵袭性和非侵袭性乳腺癌细胞体外释放明胶酶（IV型胶原酶）的差异影响。
Clin Exp Metastasis. 1997 Jul;15(4):432-9. doi: 10.1023/a:1018458406797.
10
Gynaecologic effects of tamoxifen.他莫昔芬的妇科效应。
Med Oncol. 1995 Jun;12(2):87-94. doi: 10.1007/BF01676708.