Abou-Zeid A A, Eissa A I, Salem H M
Zentralbl Bakteriol Naturwiss. 1978;133(4):362-8. doi: 10.1016/s0323-6056(78)80054-8.
Gentamicin antibiotics were produced fermentatively by Micromonospora purpurea. They were separated into gentamicin C1, C1a and C2 by paper chromatographic technique, using chloroform, methanol, and 17.0% of NH4OH (2: 1: 1 v/v) as developing solvent. The different antibiotics showed variable antimicrobial activities. The gentamicin antibiotics inhibited the biosynthesis of DNA and RNA of the proteins, present in the cells of Staphylococcus aureus.
庆大霉素类抗生素由紫色小单孢菌通过发酵产生。利用氯仿、甲醇和17.0%的氢氧化铵（2:1:1 v/v）作为展开剂，采用纸色谱技术将它们分离为庆大霉素C1、C1a和C2。不同的抗生素表现出不同的抗菌活性。庆大霉素类抗生素抑制金黄色葡萄球菌细胞中蛋白质的DNA和RNA的生物合成。
