Hominick W M, Aston A J
Parasitology. 1981 Aug;83(Pt 1):67-75. doi: 10.1017/s0031182000050046.
Pelodera strongyloides larvae were found in the conjunctival sacs of Apodemus sylvaticus and Clethrionomys glareolus and in hair follicles of A. sylvaticus. Those in the eyes were 3rd-stage larvae while most of those in the dermis were early 4th stages. There was no evidence of pathology and sections of the skin showed that the nematodes of freshly killed mice and moulted once to the adult stage in 1-2 days at 15 degrees C. The stimulus to resume development appeared to be a reduction in temperature rather than presence of bacterial food or reduction in osmotic pressure. Countless generations ensued on nutrient agar provided the nematodes were periodically sub-cultured onto fresh agar. Nematodes from the eyes died in culture. Dauerlarvae of P. strongyloides were produced in exhausted cultures. They resumed development on fresh agar but not in distilled water. About half could be induced to exsheath by a temperature similar to that of mouse skin. A. sylvaticus probably accumulates nematode larvae in the dermis during its life and the nematodes resume development when the host dies.
在林姬鼠和棕背䶄的结膜囊中以及林姬鼠的毛囊中发现了类圆线蚓幼虫。眼中的幼虫为第三期幼虫，而真皮中的大多数幼虫为早期第四期幼虫。没有病理学证据，皮肤切片显示，刚杀死的小鼠体内的线虫在15摄氏度下1 - 2天内蜕皮一次发育为成虫阶段。恢复发育的刺激因素似乎是温度降低，而非细菌食物的存在或渗透压降低。只要线虫定期转接至新鲜琼脂上，在营养琼脂上就能繁殖无数代。来自眼睛的线虫在培养中死亡。在耗尽的培养物中产生了类圆线蚓的 dauer 幼虫。它们在新鲜琼脂上恢复发育，但在蒸馏水中则不能。大约一半的 dauer 幼虫可以通过与小鼠皮肤温度相似的温度诱导脱鞘。林姬鼠在其生命过程中可能在真皮中积累线虫幼虫，宿主死亡时线虫恢复发育。
