Napier J A
Vox Sang. 1980 Dec;39(6):318-21. doi: 10.1111/j.1423-0410.1980.tb02968.x.
Serum erythropoietin has been measured before and after transfusion of blood stored in acid citrate dextrose for varying periods of time. A greater fall in erythropoietin was found following the transfusion of fresh blood than after an equal amount of stored blood in which 2,3-diphosphoglycerate concentrations were depleted. This confirms that expectations that in vivo tissue oxygenation is influenced by the oxygen affinity of transfused blood.
