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家兔对迷走神经电刺激的短潜伏期膈神经反应。

Short-latency phrenic response to electrical vagal stimulation in rabbits.

作者信息

Budzińska K, Gøowicki K, Romaniuk J R

出版信息

Acta Neurobiol Exp (Wars). 1981;41(1):87-94.

PMID:7270255
Abstract

The response of the phrenic motoneurones to single shock stimulation of- afferent vagal fibres during inspiration was studied in rabbits. The rabbits were anaesthetized with halothane, paralysed, artificially ventilated and bilaterally vagotomized. To improve the detection of the response on the non-integrated efferent phrenic activity in the presence of background discharge, 64 to 128 single responses were averaged using a sampling time of 0.1 ms. No short-latency responses were obtained to single shock at threshold strength for the coarsest afferent vagal fibres. With increased stimulus strength activating also some finer myelinated fibres, as evidenced from the effect of low-frequency stimulation on the breath duration, a short-latency inhibition followed by an enhancement was observed bilaterally. The average latency of the inhibition was 8.5 ms. The results differ from these which can be obtained in cats.

摘要

在兔身上研究了膈运动神经元在吸气期间对迷走神经传入纤维单次电刺激的反应。兔用氟烷麻醉、麻痹、人工通气并双侧迷走神经切断。为了在存在背景放电的情况下更好地检测未整合的膈传出活动的反应,使用0.1毫秒的采样时间对64至128个单次反应进行平均。对于最粗的迷走神经传入纤维,在阈值强度的单次电刺激下未获得短潜伏期反应。随着刺激强度增加,也激活了一些更细的有髓纤维,低频刺激对呼吸持续时间的影响证明了这一点,双侧观察到短潜伏期抑制后接着增强。抑制的平均潜伏期为8.5毫秒。这些结果与在猫身上获得的结果不同。

相似文献

1
Short-latency phrenic response to electrical vagal stimulation in rabbits.家兔对迷走神经电刺激的短潜伏期膈神经反应。
Acta Neurobiol Exp (Wars). 1981;41(1):87-94.
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The role of timing and magnitude of the vagal input in controlling the phrenic output in rabbits and baboons.迷走神经输入的时间和强度在控制兔和狒狒膈神经输出中的作用。
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Short-latency phrenic response to vagal stimulation after midsagittal lesion of the medulla in rabbit.兔延髓矢状面中部损伤后迷走神经刺激引起的短潜伏期膈神经反应。
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Bilateral reflex effects on phrenic nerve activity in response to single-shock vagal stimulation.单次迷走神经刺激对膈神经活动的双侧反射效应。
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Inspiratory facilitatory and inhibitory vagal influences during apnoea in rabbits.家兔呼吸暂停期间吸气性迷走神经的促进和抑制作用
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[Sustained electrical stimulation of Bötzinger complex on phrenic nerve discharges in rabbits].[持续电刺激家兔脑桥臂旁核嘴侧亚核对膈神经放电的影响]
Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2004 Nov;20(4):385-8.
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Properties of inspiratory termination by superior laryngeal and vagal stimulation.喉上神经和迷走神经刺激导致吸气终止的特性。
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Effects of vagal stimulation and carotid body chemoreceptor stimulating agents on phrenic nerve activity in vagotomized rabbits.迷走神经刺激和颈动脉体化学感受器刺激剂对迷走神经切断兔膈神经活动的影响。
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