Budzińska K, Gøowicki K, Romaniuk J R
Acta Neurobiol Exp (Wars). 1981;41(1):87-94.
The response of the phrenic motoneurones to single shock stimulation of- afferent vagal fibres during inspiration was studied in rabbits. The rabbits were anaesthetized with halothane, paralysed, artificially ventilated and bilaterally vagotomized. To improve the detection of the response on the non-integrated efferent phrenic activity in the presence of background discharge, 64 to 128 single responses were averaged using a sampling time of 0.1 ms. No short-latency responses were obtained to single shock at threshold strength for the coarsest afferent vagal fibres. With increased stimulus strength activating also some finer myelinated fibres, as evidenced from the effect of low-frequency stimulation on the breath duration, a short-latency inhibition followed by an enhancement was observed bilaterally. The average latency of the inhibition was 8.5 ms. The results differ from these which can be obtained in cats.
在兔身上研究了膈运动神经元在吸气期间对迷走神经传入纤维单次电刺激的反应。兔用氟烷麻醉、麻痹、人工通气并双侧迷走神经切断。为了在存在背景放电的情况下更好地检测未整合的膈传出活动的反应,使用0.1毫秒的采样时间对64至128个单次反应进行平均。对于最粗的迷走神经传入纤维,在阈值强度的单次电刺激下未获得短潜伏期反应。随着刺激强度增加,也激活了一些更细的有髓纤维,低频刺激对呼吸持续时间的影响证明了这一点,双侧观察到短潜伏期抑制后接着增强。抑制的平均潜伏期为8.5毫秒。这些结果与在猫身上获得的结果不同。