Karczewski W A, Nasłońska E, Romaniuk J R
Acta Neurobiol Exp (Wars). 1980;40(3):575-92.
During hyperventilation apnoea in vagotomized, anaesthetized rabbits, paralyzed and artificially ventilated, the effects of electrical afferent stimulation of the vagus nerve on the provocation and inhibition of inspiratory activity were investigated. The experiments were repeated using hyperinflation or short-lasting inflation in nonvagotomized animals. It was found that the possibility of observing inspiratory facilitatory phenomena depended on the interrelationship between the frequency of impulses transmitted separately through the thick and thin myelinated fibres. The time constants of central summation of vagal information and the possibility of observation of the phenomena of inspiratory facilitation depended on the central respiratory drive changed by CO2 and temperature.
在迷走神经切断、麻醉、麻痹并进行人工通气的家兔发生过度通气性呼吸暂停期间，研究了迷走神经传入电刺激对吸气活动激发和抑制的影响。在未切断迷走神经的动物中使用肺过度充气或短暂充气重复了这些实验。发现观察吸气易化现象的可能性取决于分别通过粗、细有髓纤维传导的冲动频率之间的相互关系。迷走神经信息中枢总和的时间常数以及观察吸气易化现象的可能性取决于由二氧化碳和温度改变的中枢呼吸驱动。
