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缺氧对人角膜上皮的影响。

The effect of anoxia on the human corneal epithelium.

作者信息

O'Leary D J, Wilson G, Henson D B

出版信息

Am J Optom Physiol Opt. 1981 Jun;58(6):472-6.

PMID:7270656
Abstract

After 6 hr of oxygen deprivation, the human corneal epithelium had not swollen. Over the first hour of recovery from anoxia, the epithelium shrank by up to 20% before returning toward its predeprivation thickness. No fluorescein staining of the epithelium was seen during these experiments, but some subjects were able to discern halos immediately after deprivation. We conclude that homeostasis is maintained in the corneal epithelium for up to 6 hr of anoxia, but the intercellular spaces may be altered.

摘要

在缺氧6小时后,人角膜上皮并未肿胀。从缺氧状态恢复的最初一小时内,上皮细胞收缩多达20%,之后才恢复到缺氧前的厚度。在这些实验过程中未观察到上皮细胞的荧光素染色,但一些受试者在缺氧后立即能察觉到光晕。我们得出结论,角膜上皮在长达6小时的缺氧状态下能维持内环境稳定,但细胞间隙可能会发生改变。

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Am J Optom Physiol Opt. 1981 Jun;58(6):472-6.
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引用本文的文献

1
Influence of hypobaric hypoxic conditions on ocular structure and biological function at high attitudes: a narrative review.低压低氧条件对高海拔地区眼部结构和生物学功能的影响:一项叙述性综述。
Front Neurosci. 2023 May 9;17:1149664. doi: 10.3389/fnins.2023.1149664. eCollection 2023.
2
Role of epithelial hyperplasia in regression following photorefractive keratectomy.上皮增生在准分子激光角膜切削术后愈合过程中的作用。
Br J Ophthalmol. 1996 Jun;80(6):545-8. doi: 10.1136/bjo.80.6.545.
3
Corneal response to rigid contact lens wear.角膜对硬性隐形眼镜佩戴的反应。
Br J Ophthalmol. 1982 Oct;66(10):667-75. doi: 10.1136/bjo.66.10.667.