Herdt T H, Stevens J B, Olson W G, Larson V
Am J Vet Res. 1981 Mar;42(3):503-6.
Statistical parameters necessary for the comparison of herd blood beta hydroxybutyrate (HB) concentration means with HB concentrations in the general population were determined in 11 clinically normal herds of Holstein-Friesian cows. These parameters were then used to compare clinically normal cows from 2 Holstein-Friesian herds experiencing a high prevalence of clinical ketosis with the normal population. Blood HB concentration means were compared with plasma glucose concentration means for their relative value as predictors of clinical ketosis prevalence within a herd. Blood HB concentration values were distributed approximately log normal and were directly related to amount of milk production. Herds with a high prevalence of clinical ketosis had blood HB log means higher (P less than 0.01) and glucose means lower (P less than 0.05) than did the normal population. Herd blood HB log means should be determined on 7 or more animals within specified production groups. When these means exceed the normal population log mean by more than 1 SD, susceptible cows in the herd may be at increased risk for the development of clinical ketosis. Blood HB log means may be of greater value than are plasma glucose concentration means for the prediction of herd ketosis prevalence.
在11个临床正常的荷斯坦 - 弗里生奶牛群中确定了将牛群血液β-羟丁酸（HB）浓度均值与普通人群中的HB浓度进行比较所需的统计参数。然后使用这些参数将来自2个临床酮病患病率高的荷斯坦 - 弗里生牛群的临床正常奶牛与正常人群进行比较。比较了血液HB浓度均值和血浆葡萄糖浓度均值作为牛群中临床酮病患病率预测指标的相对价值。血液HB浓度值近似呈对数正态分布，并且与产奶量直接相关。临床酮病患病率高的牛群的血液HB对数均值高于正常人群（P小于0.01），而葡萄糖均值低于正常人群（P小于0.05）。应在特定生产组内对7头或更多动物测定牛群血液HB对数均值。当这些均值超过正常人群对数均值超过1个标准差时，牛群中的易感奶牛发生临床酮病的风险可能会增加。对于预测牛群酮病患病率，血液HB对数均值可能比血浆葡萄糖浓度均值更有价值。
